GSTM1 and ancylostomiasis: Recombinant Ac-GST-1 was highly immunogenic and could induce not only Th2-associated antibody (IgG1) and cytokine (IL-4) responses but also a strong Th1-like response indicated by the production of IFN-γ and IgG2 antibody response, suggesting Ac-GST-1 as a possible drug and vaccine target against hookworm infection [93].