PELI1 and encephalitis: Moreover, Peli1 is emerging as a microglia-specific regulator to participate in the pathophysiological process of experimental autoimmune encephalomyelitis (EAE) [19], West Nile virus (WNV) encephalitis [23], and subarachnoid hemorrhage (SHA) [24], suggesting causative involvement of Peli1 in neuroinflammation.