As hormone-secreting pituitary adenomas, prolactinoma (excess of prolactin), Cushing’s disease (excess of ACTH) and acromegaly (excess of growth hormone) are the most prevalent types, although non-functional pituitary adenomas which lack hormone overproduction, affect a large number of patients worldwide, and their diagnosis is more challenging [26]. The gene discussed is POMC; the disease is pituitary gland adenoma.