In this study, the median (IQRs) level of PLT of patients with gynecological cancer was 261.5 (219.0‐314.3) × 109/L, and 15% of the patients had thrombocytosis, which was in accordance with previous literature.8, 21, 26 According to the existing studies, the increase in PLT is due to tumor‐secreted cytokines (including interleukin (IL)‐1, IL‐3, IL‐6, and leukemia inhibitory factors) that play a role in stimulating megakaryocyte growth and thrombopoiesis.21 But we found that increased PLT occurred not only in gynecological malignant tumors, but also in benign gynecological tumors. This evidence concerns the gene IL6 and benign female reproductive system neoplasm.