Three different epithelial phenotypic patterns were observed in most tumours of our series of ASCAP cases (Figs. 1, 2, 3 and Supplementary Figs. 2, 3): (1) Areas with pure adenocarcinoma resembling pancreatobiliary-type adenocarcinomas of PDAC was characterized by the expression of K8/18, K7, MUC5AC, MUC1, and CEA. This evidence concerns the gene MUC5AC and adenocarcinoma.