Meanwhile, growing evidences have confirmed that, some inflammatory cytokines, such as IL-10, IL-1β, IFN-γ and TNF-α, may be responsible for the pathogenesis of atherosclerosis because these cytokines can result in the adhesion of leukocytes to vascular endothelium and foam cell formation [30, 31]. The gene discussed is IFNG; the disease is atherosclerosis.