IL18 and acute kidney injury: Although significant improvements in investigating novel markers of AKI were recently reached, such as kidney injury molecule-1 (KIM-1), neutrophil gelatinase associated lipocalin-2 (NGAL) or Interleukin 18 (IL-18) (all mirroring injuries of proximal tubules), their incorporation into routine clinical practice is hindered by inconsistent results between different studies [2].