To investigate the role of MK2 in glioblastoma cell proliferation and in response to temozolomide, we first confirmed that temozolomide activates MK2 (p-MK2, Figure 2A) and MK2 down-stream target Hsp27 (p-Hsp27, Figure 2B). The gene discussed is MAPKAPK2; the disease is glioblastoma.