GAPDH and hepatocellular carcinoma: The expression of key rate-limiting enzymes, such as glucose transporter 1 (GLUT1), hexokinases (HKs), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), pyruvate kinase, and lactate dehydrogenase (LDHA), were enhanced, and promoted glycolysis of hepatocytes during HCC progression [23].