Hsp70-specific antibody (cmHsp70.1) and survivin-targeting miRNA plasmid-loaded human serum albumin (HSA) NPs (180 nm–220 nm) significantly reduced survivin expression and enhanced caspase 3/7 activity in U87 MG and LN229 glioblastoma cells under irradiation [164]. The gene discussed is BIRC5; the disease is glioblastoma.