Interestingly, a defective expression of GLT-1 in BG, associated with PCs hyperexcitation and motor impairments, was also reported in a mouse model of myotonic dystrophy type 1 (DM1), a multisystemic disorder in which cerebellar abnormalities are implicated [94]. The gene discussed is SLC1A2; the disease is myotonic dystrophy type 1.