SLC1A3 and Esophageal atresia: Indeed, the ablation in mice of the SLC1A3 gene, coding for the GLAST transporter, results in severe motor impairments and several missense mutations, either inherited or de novo, in the GLAST gene were shown to cause distinct forms of episodic ataxia (EA), whose symptoms severity appeared sometimes correlated with the extent of glutamate transporter dysfunction (Table 2) [88,89,90,91,92,93].