MUC4 and colorectal carcinoma: In our MUC4 promoter analysis data, we observed three putative TCF/LEF binding sites, suggesting its regulation through Wnt/β-catenin signaling and indicating that reduction of MUC4 at the transcript as well as protein levels occurs, suppressing the Notch pathway effector Hath1 by Wnt/β-catenin pathway in CRC [120].