CFL1 and neoplasm: Co‐ordinated reorganization of the actin cytoskeleton is essential to tumour invasion and metastasis.5, 6, 7 LIM kinase 1 (LIMK1) is one of the members of the LIM kinase protein family.6, 8 Previous studies6, 8, 9, 10, 11 demonstrated that LIMK played an essential role in regulating the polymerization of actin through phosphorylation and inactivation of cofilin, which acted as the only downstream effector of LIMK1.