Previous studies have identified glypican 3 (GPC3), Golgi protein-73 (GP73), descarboxyprothrombin (DCP), glutamic—pyruvic transaminase (GPT) and gamma-glutamyl carboxylase (GGCX) as complementary biomarkers for HCC diagnosis [17–19]. This evidence concerns the gene GGCX and hepatocellular carcinoma.