APEX1 and hepatocellular carcinoma: As shown in Figure 8E–8F, grade 1 or stage 1 HCC patients in the high APEX1 expression group were associated with worse OS (grade 1 HCC: HR=2.83, log-rank p=0.042; stage 1 HCC: HR=2.19; log-rank p=0.018) compared to those in the low APEX1 expression group.