APEX1 and hepatocellular carcinoma: Moreover, the AUC value for AFP was 0.5874 (95%CI, 0.53 to 0.64; p=0.003), which was significantly lower than the AUC value of 0.7378 for APEX1 (95%CI, 0.69 to 0.79, p<0.0001) for the HCC samples (Figure 4E).