CDC5L has been confirmed by many studies to act as a transcription factor to exert biological functions.28, 29, 30, 31 Li et al34 confirmed that, as a transcription factor, CDC5L in prostate cancer cells directly interacted with the long noncoding RNA nuclear‐enriched abundant transcript 1 (NEAT1) for mutual positive regulation. This evidence concerns the gene CDC5L and Familial prostate cancer.