MYC, EZH2 and SOX9 are known to be repressed in response to BET inhibition in several malignancies, such as medulloblastoma, bladder cancer and myelofibrosis [14, 38–40], but as yet the effect of JQ1 on these genes in TNBC has not been explored. The gene discussed is EZH2; the disease is urinary bladder cancer.