SLC6A14 and ischemic colitis: SLC6A14 expression was also increased in rectal and colonic biopsies from patients with ulcerative colitis or infectious/ischemic colitis compared to controls, suggesting that SLC6A14 upregulation might be the result of the inflammatory context rather than a specific pathophysiological consequence of the ulcerative colitis [41, 59, 60, 68].