BRCA2 and ovarian cancer: Regarding weight status and weight change, after adjusting for age at menarche, parity, oral contraceptives, height, and hormone replacement therapy, McGee and colleagues [21] case-control study did not observe a significant association between current weight status or weight change throughout adulthood and diagnosis of ovarian cancer among 403 women with BRCA1 and 66 women with BRCA2 pathogenic germline gene variants.