The markers that were evaluated included: CD34, which can either be increased if budding off of immature megakaryoblasts (i.e. immature platelet fraction) or can be decreased if platelets are activated, Draq5+ which may be present in some platelets if platelet-formation results in DNA-containing platelets, His3, which we hypothesize to be increase in patients with sepsis, and Draq5+His3+ cells, which may indicate that His3 and DNA are bound together within the platelet. The gene discussed is CD34; the disease is Sepsis.