Type I IFN score and expression levels of the nine genes—BATF2, LAMP3, CD83, TNFSF10, CLEC4A, IDO1, STAT1, STAT2, and IRF7—may serve as biomarkers for predicting the clinical responses to ABA treatment in patients with RA. The gene discussed is TNFSF10; the disease is rheumatoid arthritis.