And miR-UL112-3p down-regulates the level of BclAF1 (Bcl-2-associated transcription factor 1, a protein that restricts HCMV immediate early gene expression and spread) during the late phase of infection, thus, the absence of BclAF1 neutralization leads to inhibited viral gene expression and replication [15]. Here, BCLAF1 is linked to infection.