In our cohort, T-ALL comprised 18.6% (n = 26) of ALL patients, and the most commonly mutated genes included NOTCH1 (23.1%), FBXW7 (23.1%), PHF6 (11.5%), PTEN (11.5%) and JAK1 (7.7%). The gene discussed is FBXW7; the disease is acute lymphoblastic leukemia.