In our cohort, T-ALL comprised 18.6% (n = 26) of ALL patients, and the most commonly mutated genes included NOTCH1 (23.1%), FBXW7 (23.1%), PHF6 (11.5%), PTEN (11.5%) and JAK1 (7.7%). This evidence concerns the gene NOTCH1 and acute lymphoblastic leukemia.