The highest post-test probability of dengue for positive test was achieved by SD IgM RDT at 96.2% (95%CI 90.4–98.5), followed by SD NS1 RDT and SD NS1/IgM RDT at 95.1% (95%CI 89.8–97.7) and 94.9% (95%CI 90.8–97.3), respectively. Here, CD40LG is linked to dengue disease.