KRAS and colorectal cancer: To evaluate the effect of miR-31-3p, miR-143 and miR-145 on the c-MYC expression in colorectal cancer, we deregulated these miRs in two anti-EGFR resistant cell lines: KRAS mutated (p.G13D) HCT116 and KRAS mutated (p.G12V) SW480 cell line [21].