As already alluded to, the BMI (kg/m2), glycemia (mM), insulinemia (μU/mL), plasma C-peptide concentration (ng/mL), HOMA-IR (mM.μU/mL), HbA1C (percent), TC (g/L), HDL-C (g/L), LDL-C (g/L), TGs (g/L), leptin (ng/mL), adiponectin (μg/mL), IL-6 (pg/mL), TNF-α (pg/mL), hs-CRP (ng/L) and GLP- 1 (pmol/L) were measured in 60 male and 40 female subjects aged between 30 and 40 years and affected by the MetS. This evidence concerns the gene LEP and metabolic syndrome.