IL6 and myocardial infarction: This cytokine could drive protective response in the short term in myocardial infarction but sustained elevated level of IL‐6 damages to the heart by resulting in chronic inflammation and fibrotic pathology.20 Several in vivo studies using IL‐6 knockout mice come to a divergence because both the negative21, 22 and positive23 effects of this genetic manipulation on the development of cardiac remodelling and dysfunction were observed.