The results in the study by Lai et al22 showed no significant effect of deletion of IL‐6 on LV remodelling and dysfunction after 2‐ and 4‐week TAC but Zhao et al23 reported that deletion of IL‐6 ameliorates left ventricular hypertrophy, fibrosis and dysfunction in mice with a longer follow‐up (6 weeks) after TAC. Here, IL6 is linked to persistent truncus arteriosus.