AKT1 and diabetes mellitus: A novel finding of our study was that in AKAP150−/− DM mice compared to WT DM mice, aortic remodelling and fibrosis were inhibited by the up‐regulation of BK‐β1 expression, Akt phosphorylation at Ser473 and the expression of p‐GSK3β (Figures 2C and5A).