AKAP150 anchors CaN and mediates nuclear factor of activated T cells c3 (NFATc3) activation and the transcriptional suppression of regulatory BK‐β1 subunits under hyperglycaemic conditions.12 During hyperglycaemia and diabetes, enhanced vascular tone results from impaired BK channels, and the process depends on the combination between CaN and AKAP150. Here, KCNMA1 is linked to Hyperglycemia.