CASP3 and non-small cell lung carcinoma: Resveratrol-loaded gelatin NPs can suppress the viability and proliferation of non-small cell lung cancer (NSCLC) cells by upregulation of BAX, p53, p21, caspase-3, and down-regulation of Bcl-2 and nuclear factor-κB (NF-κB) demonstrating the involvement of mitochondrial-mediated apoptosis [224].