On multivariate analysis, high KL-6 level (odds ratio [OR], 5.173; 95% CI, 1.640–16.320; P = 0.005) and older age (OR, 1.104; 95% CI, 1.030–1.184; P = 0.005) were independently associated with a UIP pattern (Table 2). The gene discussed is MUC1; the disease is idiopathic pulmonary fibrosis.