CASP3 and thyroid gland carcinoma: To test the link between ARV-825-induced apoptosis activation and cytotoxicity in thyroid carcinoma cells, the apoptosis inhibitors were utilized, including the caspase-3 specific inhibitor z-DEVD-fmk, the caspase-9 inhibitor z-LEHD-fmk and the pan-caspase inhibitor z-VAD-fmk.