ARID1A and Cirrhosis: When ARID1A mutations were examined for correlations with HCC clinical characteristics, the results suggested that ARID1A alteration is correlated with larger HCC size and well or moderately differentiated HCC, but not with patient age, sex, cirrhosis, tumour node metastasis (TNM) stage, tumour size, number of tumours, vascular invasion, patient survival, HBV infection, hepatitis C virus (HCV) infection, heavy alcohol consumption and diabetes mellitus (Table 2).78