In the context of HCC, Tordella et al89 identified that ARID1B serves as a regulator of oncogene‐induced senescence (OIS) and represents a potent tumour suppressor mechanism; they described that knock‐down of ARID1B prevented OIS and cooperated with RAS to induce liver tumours. This evidence concerns the gene ARID1B and hepatocellular carcinoma.