STAT3 and hepatocellular carcinoma: As mentioned earlier, Fang et al demonstrated that steatohepatitis and HCC development were observed in hepatocyte‐specific Arid1a knockout mice, which was accompanied by infiltration of innate immune cells (including F4/80+ macrophages and CD11c+ neutrophil cells) into the liver parenchyma and increased levels of tumour necrosis factor (TNF)‐α and interleukin (IL)‐6, as well as activation of the STAT3 and NF‐κB pathways.