Mutations in some subunits, such as those in ARID2 mentioned earlier, may cause hepatocarcinogenesis associated with DNA damage and repair, while deletions in other subunits, such as SMARCB1, may not cause cancer via defects in DNA repair but rather due to epigenetic alterations such as disruption of chromatin‐based contributions to the control of cell fate.58 This evidence concerns the gene ARID2 and cancer.