SMARCA4 and Hepatic fibrosis: Furthermore, SMARCA4, which is found to facilitate S‐phase entry and attenuate apoptosis, also promotes cell proliferation through the up‐regulation of SMAD6. On the other hand, it has been shown that SMARCA4 aggravates liver fibrosis through regulating the activation of hepatic stellate cells (HSCs) via the transforming growth factor beta (TGFβ)/SMAD signalling pathway.57