As mentioned earlier, Fang et al demonstrated that steatohepatitis and HCC development were observed in hepatocyte‐specific Arid1a knockout mice, which was accompanied by infiltration of innate immune cells (including F4/80+ macrophages and CD11c+ neutrophil cells) into the liver parenchyma and increased levels of tumour necrosis factor (TNF)‐α and interleukin (IL)‐6, as well as activation of the STAT3 and NF‐κB pathways. The gene discussed is TNF; the disease is hepatocellular carcinoma.