The DYS-HAC was transferred to Duchenne muscular dystrophy patient-derived fibroblasts from CHO cells, from which iPSCs were generated using a combination of lentiviral infection for expressing mouse SLC7A1 and retroviral infection for expressing KLF4, SOX2, OCT4, and c-MYC [28]. The gene discussed is POU5F1; the disease is Duchenne muscular dystrophy.