GFPT1 and cancer: When searching with the initial compound as beta-D-fructofuranose 6-phosphate and the terminal compound as L-glutamate (maximum number of reactions: 8, weight measurement: mean, search criterion: bottleneck, cancer type: BLCA), the direct biochemical reaction from beta-D-fructofuranose 6-phosphate to the L-glutamate, which is catalyzed by GFPT1, ranks at the top (Figure 6).