Hemoglobin (119.3 ± 19.2 vs. 113.9 ± 21.6 g/l, P=0.001) and HDL-cholesterol (1.1 ± 0.3 vs. 1.0 ± 0.3 mmol/L, P=0.001) were significantly lower, whereas creatinine levels (138.0 ± 106.8 vs. 96.6 ± 68.1 μmol/l, P < 0.001) and NT-proBNP (887.3 [290.0–2656.2] vs. 1704.0 [536.6–5077.2], P < 0.001) were significantly higher in the hyperuricemia group than in normal sUA group. This evidence concerns the gene NPPB and hyperuricemia.