Rather, our results of higher expression of STAT1/pSTAT1 and CD107a expression accompanied by lower pSTAT4 expression and cytokine production at baseline in HCV patients with cirrhosis are in line with data published by Ahlenstiel et al. describing a polarized NK cell phenotype toward cytotoxicity away from IFN-γ production (9). The gene discussed is IFNG; the disease is Cirrhosis.