KLRC1 and cirrhosis of liver: To investigate the impact of the DAA-mediated rapid elimination of HCV and the potential role of liver cirrhosis on NK cell phenotype and function restoration, we first analyzed circulating NK subpopulation frequencies (CD56dim and CD56bright subsets) and their receptor profile on the basis of the frequencies and expression levels of activating (HLA-DR, NKp46, and NKp30) and inhibitory (KIR2DL2/L3, NKG2A, and CD85j) receptors.