Ex vivo degranulating CD107a+ CD56dim cells were also found at an increased frequency at baseline in HCV patients with cirrhosis compared with healthy (P = 0.002) and non-HCV cirrhotics (P = 0.005) (Figures 5F,G) and once again normalized by FU48 (P < 0.0001) (Figure 5G, right graph). This evidence concerns the gene LAMP1 and Cirrhosis.