IFNG and Cirrhosis: Similar to that observed in the CD56bright subset, the frequency of IFN-γ+ CD56dim cells was lower in HCV patients compared with healthy subjects (P < 0.0001 in HCV cirrhotics and P = 0.003 in non-cirrhotics), even though it was significantly higher in patients without cirrhosis than in those with cirrhosis (P = 0.001) (Figures 6A,C).