The ROC analysis revealed that optimal cutoff values for predicting bacteremic UTI of CRP and DNI alone were DNI alone >1.2% (AUC, 0.727; 95% CI, 0.684–0.768; P < 0.001; sensitivity, 61.8%; specificity, 77.9%; negative predictive value [NPV], 96.3%; positive predictive value [PPV], 18.1%) and CRP alone >45.1 mg/L (AUC, 0.680; 95% CI, 0.635–0.723; P < 0.001; sensitivity, 70.6%; specificity, 62.0%; NPV; 96.4% PPV, 12.9%), respectively (Supplementary Table S1 and Supplementary Fig. S1). The gene discussed is CRP; the disease is bacterial urinary tract infection.