To investigate the impact of CNOT7 knockdown on the sensitivity of HCC cells to NK‐92MI cell cytolysis, we cocultured HepG2shCNOT7, HepG2ns and HepG2 cells with NK‐92MI cells at a 1 : 10 E:T ratio for 12 h. Here, CNOT7 is linked to hepatocellular carcinoma.