Higher death rates of mDANs from PD Dupl patients compared with Ctrl mDANs are in accordance with previous data: iPSC-based studies, comparing mDNAs generated from Ctrl and familial PD patients with either SNCA triplication or point mutations in the genes LRRK2, PARKIN or PINK1, also pointed out an increased neuronal death and elevated susceptibility of mDANs to dopamine-induced oxidative stress in PD mDNAs (40–44). The gene discussed is LRRK2; the disease is Parkinson disease.