[39–41] Other biomarkers, including hs-cTnT, Galectin-3, growth factors and models that include several biomarkers have shown to be associated with AS and correlate with prognosis.[39] Our results suggest that urea level, a simple and routinely used blood test, may serve as a useful biomarker in patients with AS. The gene discussed is LGALS3; the disease is aortic stenosis.