MAPK1 and Familial prostate cancer: We also correlated the selected genes with chromosomal regionscommonly deleted in prostate cancer, such as 10q23, which contains thePTEN/HHEX/MXI1 gene cluster,and 22q11.21, harboring the MAPK1 gene, found 20 genes mutated in at least 5% ofthree patient cohorts and six genes affecting patient survival when mutated.