Additionaly, we found the Mapk1 gene, whose homologMAPK1 maps to 22q11.21, in a region between the 22q11.21 and22q12.1 segments deleted in 29% and 33% of intermediate risk tumors, respectively,but not frequently observed in high risk cancers (Ishkanian et al., 2009). The gene discussed is MAPK1; the disease is cancer.