Furthermore, in a mouse model of Parkinson’s disease, the expression of VGLUT1 increases with the loss of dopamine; However, a significant decrease in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induction and an increase in VGLUT1 in the dorsolateral (DL) striatum. The gene discussed is SLC17A7; the disease is Parkinson disease.