Continuous linear growth, tall stature, eunuchoid body proportion.  Genu valgum, kyphoscoliosis, pectus carinatus.  Cisgender, heterosexual, and normal libido.  Normal genitalia and testicular volume Increased serum basal testosterone and FSH, normal serum LH levels. Azoospermia  Obesity. Insulin resistance. Osteoporosis. The gene discussed is BRD2; the disease is osteoporosis.