As FOXG1 is also observed to be dysregulated in various types of cancer including hepatoblastoma, medulloblastoma, breast cancer, and ovarian cancer (Adesina et al., 2007; Chan et al., 2009; Li et al., 2013), it is plausible that aberrant regulation of FOXG1 expression outside of the nervous system also triggers dysregulated cell cycle and tumorigenesis in pathological conditions. The gene discussed is FOXG1; the disease is hepatoblastoma.