It also upregulated integrins (ICAM‐1) and growth factors (HGF, EFG) in the sonicated tissue and reduced histological signs of kidney damage.61 Wu et al developed microbubbles loaded with SDF‐1.105 Infusion of the SDF‐1‐loaded microbubbles followed by focused ultrasound to the kidney enhanced MSC homing 1.8‐fold compared with normal microbubbles and 6.6‐fold over ultrasound alone. Here, CXCL12 is linked to Nephropathy.