However, it has been reported that lncRNA NEAT1 can affect glioblastoma cell growth and invasion by inducing trimethylation of H3K27 in the promoter regions of Axis inhibition protein 2, inhibitor of β-catenin and T cell factor, and glycogen synthase kinase 3B or by regulating EZH2 levels11. The gene discussed is EZH2; the disease is glioblastoma.