Through in-depth studies, many scholars have discussed the detailed roles of TP537, CTNNB17, TERT8, ARID1A, RB1, CDKN2A9,14, CCND1, AXIN19, ARID210, PTEN13 and other common mutant genes15 in the occurrence, development, recurrence and prognosis of HCC. Here, CCND1 is linked to hepatocellular carcinoma.