As expected, consecutive IPA canonical pathway analysis displayed predominant modulation of EMT-pathway-related genes and genes implicated in ovarian cancer signaling, as genes related to other major EMT-related pathways (including the Wnt/β-catenin, the Wnt/Ca2+, and the TGF-β pathways) similarly exhibited significant DNA methylation alterations (see Figure 3B and Table A1). The gene discussed is TGFB1; the disease is ovarian cancer.