Recently, Jreige et al. described that the metabolic-to-morphological volume ratio (MMVR)—calculated by dividing MTV by morphological tumor volume (MoTV)—was able to predict the radiological response to anti-PD-1/PD-L1 blockade and was negatively correlated with tumor PD-L1 expression and tumor necrosis [18]. Here, CD274 is linked to neoplasm.