Figure S1B shows the expression of HSP90 AA1 and PIK3CA in normal human skin. In addition, we also analyzed sequences from patients with skin cutaneous melanoma in the cBioPortal database [30,31,32,33,34]. We found that 10% and 19% patients had mutations or dysregulated expression on HSP90AA1 and PIK3CA, respectively (Figure S1C). The gene discussed is PIK3CA; the disease is cutaneous melanoma.