IGHE and congenital rubella syndrome: The number of cytoplasmic IgE-positive mast cells was also significantly correlated to radiological severity of CRS (r = 0.280, p = 0.012; Figure 6H), peripheral blood eosinophilia (r = 0.404, p < 0.001; Figure 6I), and total serum IgE (r = 0.500, p < 0.001; Figure 6J).